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Checks and Balances: IL-23 in the Intestine.

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Huber S, Flavell RA

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Checks and Balances: IL-23 in the Intestine.

Immunity. 2010 Aug 27;33(2):150-152

Authors: Huber S, Flavell RA

In this issue of Immunity, Ahern et al. (2010) show that IL-23R signaling in CD4(+) T cells induces effector and suppresses regulatory CD4(+) T cells, which is critical for the development of intestinal, but not systemic, inflammation.

PMID: 20732638 [PubMed - as supplied by publisher]

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