Huber S, Flavell RA
Checks and Balances: IL-23 in the Intestine.
Immunity. 2010 Aug 27;33(2):150-152
Authors: Huber S, Flavell RA
In this issue of Immunity, Ahern et al. (2010) show that IL-23R signaling in CD4(+) T cells induces effector and suppresses regulatory CD4(+) T cells, which is critical for the development of intestinal, but not systemic, inflammation.
PMID: 20732638 [PubMed - as supplied by publisher]