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The Hunt for iNKT Cell Antigens: alpha-Galactosidase-Deficient Mice to the Rescue?

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Van Kaer L, Joyce S

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The Hunt for iNKT Cell Antigens: alpha-Galactosidase-Deficient Mice to the Rescue?

Immunity. 2010 Aug 27;33(2):143-145

Authors: Van Kaer L, Joyce S

The endogenous lipids that control the functions of invariant natural killer T (iNKT) cells remain enigmatic. In this issue of Immunity, Darmoise et al. (2010) report that lysosomal alpha-galactosidase A destroys self-antigens recognized by iNKT cells.

PMID: 20732635 [PubMed - as supplied by publisher]

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