Fidelity of Pathogen-Specific CD4+ T Cells to the Th1 Lineage Is Controlled by Exogenous Cytokines, Interferon-? Expression, and Pathogen Lifestyle

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CELL HOST AND MICROBE

Meredith M. Curtis, Emily Rowell, Shahin Shafiani, Amina Negash, Kevin B. Urdahl, Christopher B. Wilson, Sing Sing Way. The degree of lineage stability achieved by pathogen-specific CD4⁺ T cells in vivo, and how this impacts host defense against infection, remains unclear. We demonstrate that in response....