Kawasaki K, Manabe T
Latency of the Lipid A Deacylase PagL Is Involved in Producing a Robust Permeation Barrier in the Outer Membrane of Salmonella enterica.
J Bacteriol. 2010 Nov;192(21):5837-40
Authors: Kawasaki K, Manabe T
Lipid A deacylase PagL, which detoxifies endotoxin, is latent in Salmonella enterica. This study determined the biological significance of this latency. PagL latency was beneficial for bacteria in producing a robust permeation barrier through lipid A modifications under host-mimetic conditions that induced the modification enzymes, including PagL.
PMID: 20833808 [PubMed - in process]