Shailesh S Kantak
Neural substrates of motor memory consolidation depend on practice structure
Nature Neuroscience 13, 923 (2010). doi:10.1038/nn.2596
Authors: Shailesh S Kantak, Katherine J Sullivan, Beth E Fisher, Barbara J Knowlton & Carolee J Winstein
Motor-skill practice drives subsequent offline activity in functionally related resting human brain networks. We investigated the manner in which offline neural networks are modulated by practice structures that affect motor-skill retention. Interference to dorsolateral-prefrontal cortex (DLPFC), but not to primary motor cortex (M1), after variable practice attenuated motor-skill retention, whereas interference to M1, but not to DLPFC, after constant practice attenuated motor-skill retention. We conclude that neural substrates of motor-memory consolidation are modulated by practice structure.