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The Combination of Rifampin plus Moxifloxacin Is Synergistic for Suppression of Resistance but Antagonistic for Cell Kill of Mycobacterium tuberculosis as Determined in a Hollow-Fiber Infection Model.

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The Combination of Rifampin plus Moxifloxacin Is Synergistic for Suppression of Resistance but Antagonistic for Cell Kill of Mycobacterium tuberculosis as Determined in a Hollow-Fiber Infection Model.
MBio. 2010;1(3)… . . . → Read More: The Combination of Rifampin plus Moxifloxacin Is Synergistic for Suppression of Resistance but Antagonistic for Cell Kill of Mycobacterium tuberculosis as Determined in a Hollow-Fiber Infection Model.

The Pseudomonas aeruginosa Exopolysaccharide Psl Facilitates Surface Adherence and NF-kappaB Activation in A549 Cells.

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The Pseudomonas aeruginosa Exopolysaccharide Psl Facilitates Surface Adherence and NF-kappaB Activation in A549 Cells.
MBio. 2010;1(3):
Authors: Byrd MS, Pang B, Mishra M, Swords WE, Wozniak DJ
In or… . . . → Read More: The Pseudomonas aeruginosa Exopolysaccharide Psl Facilitates Surface Adherence and NF-kappaB Activation in A549 Cells.

Inferring the Evolutionary History of the Plant Pathogen Pseudomonas syringae from Its Biogeography in Headwaters of Rivers in North America, Europe, and New Zealand.

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Inferring the Evolutionary History of the Plant Pathogen Pseudomonas syringae from Its Biogeography in Headwaters of Rivers in North America, Europe, and New Zealand.
MBio. 2010;1(3):
Authors: Morris CE, San… . . . → Read More: Inferring the Evolutionary History of the Plant Pathogen Pseudomonas syringae from Its Biogeography in Headwaters of Rivers in North America, Europe, and New Zealand.

Indirect Pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in Polymicrobial Otitis Media Occurs via Interspecies Quorum Signaling.

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Indirect Pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in Polymicrobial Otitis Media Occurs via Interspecies Quorum Signaling.
MBio. 2010;1(3):
Authors: Armbruster CE, Hong W, Pang B, Wei… . . . → Read More: Indirect Pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in Polymicrobial Otitis Media Occurs via Interspecies Quorum Signaling.

Comparative analyses of the bacterial microbiota of the human nostril and oropharynx.

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Comparative analyses of the bacterial microbiota of the human nostril and oropharynx.
MBio. 2010;1(3):
Authors: Lemon KP, Klepac-Ceraj V, Schiffer HK, Brodie EL, Lynch SV, Kolter R
The nose and throa… . . . → Read More: Comparative analyses of the bacterial microbiota of the human nostril and oropharynx.

The endolysins of bacteriophages CMP1 and CN77 are specific for the lysis of Clavibacter michiganensis strains.

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The endolysins of bacteriophages CMP1 and CN77 are specific for the lysis of Clavibacter michiganensis strains.
Microbiology. 2010 Aug;156(Pt 8):2366-73
Authors: Wittmann J, Eichenlaub R, Dreiseikelmann B
. . . → Read More: The endolysins of bacteriophages CMP1 and CN77 are specific for the lysis of Clavibacter michiganensis strains.

Class IIa bacteriocin resistance in Enterococcus faecalis V583: The mannose PTS operon mediates global transcriptional responses.

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Class IIa bacteriocin resistance in Enterococcus faecalis V583: The mannose PTS operon mediates global transcriptional responses.
BMC Microbiol. 2010 Aug 25;10(1):224
Authors: Opsata M, Nes IF, Holo H
. . . → Read More: Class IIa bacteriocin resistance in Enterococcus faecalis V583: The mannose PTS operon mediates global transcriptional responses.

The liposoluble proteome of Mycoplasma agalactiae: an insight into the minimal protein complement of a bacterial membrane.

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The liposoluble proteome of Mycoplasma agalactiae: an insight into the minimal protein complement of a bacterial membrane.
BMC Microbiol. 2010 Aug 25;10(1):225
Authors: Cacciotto C, Addis MF, Pagnozzi D, Che… . . . → Read More: The liposoluble proteome of Mycoplasma agalactiae: an insight into the minimal protein complement of a bacterial membrane.

Immune regulation of a chronic bacteria infection and consequences for pathogen transmission.

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Immune regulation of a chronic bacteria infection and consequences for pathogen transmission.
BMC Microbiol. 2010 Aug 25;10(1):226
Authors: Pathak AK, Creppage KE, Werner JR, Cattadori IM
ABSTRACT: B… . . . → Read More: Immune regulation of a chronic bacteria infection and consequences for pathogen transmission.

The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis.

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The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis.
BMC Microbiol. 2010 Aug 26;10(1):227
Authors: Forslund AL, Naslund Salomonsson E, Golovliov I, Kuoppa … . . . → Read More: The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis.

Involvement of TIP60 acetyltransferase in intracellular Salmonella replication.

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Involvement of TIP60 acetyltransferase in intracellular Salmonella replication.
BMC Microbiol. 2010 Aug 26;10(1):228
Authors: Wang X, Li D, Qu D, Zhou D
ABSTRACT: BACKGROUND: Salmonella enterica is a… . . . → Read More: Involvement of TIP60 acetyltransferase in intracellular Salmonella replication.

Genes and pathways for CO2 fixation in the obligate, chemolithoautotrophic acidophile, Acidithiobacillus ferrooxidans.

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Genes and pathways for CO2 fixation in the obligate, chemolithoautotrophic acidophile, Acidithiobacillus ferrooxidans.
BMC Microbiol. 2010 Aug 27;10(1):229
Authors: Esparza M, Cardenas JP, Bowien B, Jedlicki… . . . → Read More: Genes and pathways for CO2 fixation in the obligate, chemolithoautotrophic acidophile, Acidithiobacillus ferrooxidans.

Proteomic identification of secreted proteins of Propionibacterium acnes.

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Proteomic identification of secreted proteins of Propionibacterium acnes.
BMC Microbiol. 2010 Aug 27;10(1):230
Authors: Holland C, Mak TN, Zimny-Arndt U, Schmid M, Meyer TF, Jungblut PR, Brueggemann H
. . . → Read More: Proteomic identification of secreted proteins of Propionibacterium acnes.

Global gene expression under nitrogen starvation in Xylella fastidiosa: contribution of the sigma54 regulon.

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Global gene expression under nitrogen starvation in Xylella fastidiosa: contribution of the sigma54 regulon.
BMC Microbiol. 2010 Aug 28;10(1):231
Authors: da Silva Neto JF, Koide T, Gomes SL, Marques MV
. . . → Read More: Global gene expression under nitrogen starvation in Xylella fastidiosa: contribution of the sigma54 regulon.

Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.

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Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.
J Exp Med. 2010 Aug 30;207(9):1843-51
Authors: Schaefer A, Im HI, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny P… . . . → Read More: Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.

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Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.
J Exp Med. 2010 Aug 30;207(9):2003-17
Authors: Sundling C, Forsell MN, O’Dell S, Feng Y, Chakrabarti B… . . . → Read More: Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells.

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IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells.
J Exp Med. 2010 Aug 30;207(9):1871-8
Authors: Grinberg-Bleyer Y, Baeyens A, You S, Elhage R, Fourcade… . . . → Read More: IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells.

Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness.

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Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness.
J Exp Med. 2010 Aug 30;207(9):1995-2002
Authors: Pietzsch J, Scheid JF, Mouquet H, Klein F, Seaman MS… . . . → Read More: Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness.

Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints.

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Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints.
J Exp Med. 2010 Aug 30;207(9):1879-89
Authors: Nishio J, Feuerer M, Wong J, Mathis D, Benoist C… . . . → Read More: Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints.

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity.

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MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity.
J Exp Med. 2010 Aug 30;207(9):1891-905
Authors: Irla M, Küpfer N, Suter T, Lissilaa R, B… . . . → Read More: MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity.

Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology.

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Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology.
J Exp Med. 2010 Aug 30;207(9):1907-21
Authors: Hao J, Liu R, Piao W, Zhou Q, Vollmer TL, Campa… . . . → Read More: Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology.

Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.

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Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.
J Exp Med. 2010 Aug 30;207(9):1835-41
Authors: Shih HY, Krangel MS
Studies have suggested that antigen rec… . . . → Read More: Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.

Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response.

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Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response.
J Exp Med. 2010 Aug 30;207(9):1981-93
Authors: Markowska AI, Liu FT, Panjwani N
Recent studies have shown that a ca… . . . → Read More: Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response.

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function.

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A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function.
J Exp Med. 2010 Aug 30;207(9):1967-79
Authors: Falet H, Pollitt AY, Begonja AJ, Weber SE, Duerschmie… . . . → Read More: A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function.

The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation.

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The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation.
J Exp Med. 2010 Aug 30;207(9):2033-41
Authors: Park B, Spooner E, Houser BL, Strominger JL, Ploegh HL
Human cytomegalovi… . . . → Read More: The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation.

Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice.

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Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice.
J Exp Med. 2010 Aug 30;207(9):1863-70
Authors: Kim HK, Cheng AG, Kim HY, Missiakas DM, Schneewind O
. . . → Read More: Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice.

Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation.

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Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation.
J Exp Med. 2010 Aug 30;207(9):2019-31
Authors: Fafi-Kremer S, Fofana I, Soulier … . . . → Read More: Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation.

CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses.

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CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses.
J Exp Med. 2010 Aug 30;207(9):1951-66
Authors: Zhou J, Tang P… . . . → Read More: CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses.

Estrogen promotes cutaneous wound healing via estrogen receptor {beta} independent of its antiinflammatory activities.

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Estrogen promotes cutaneous wound healing via estrogen receptor {beta} independent of its antiinflammatory activities.
J Exp Med. 2010 Aug 30;207(9):1825-33
Authors: Campbell L, Emmerson E, Davies F, Gillive… . . . → Read More: Estrogen promotes cutaneous wound healing via estrogen receptor {beta} independent of its antiinflammatory activities.

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.

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PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.
J Exp Med. 2010 Aug 30;207(9):1853-62
Authors: Li P, Li M, Lindberg MR, Kennett MJ, Xiong N, Wang Y
Neu… . . . → Read More: PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.

DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.

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DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.
J Exp Med. 2010 Aug 30;207(9):1939-50
Authors: Lai AY, Fatemi M, Dhasarathy A, Malone C, Sobol SE, Geigerman C, Jaye… . . . → Read More: DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.

Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.

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Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.
J Exp Med. 2010 Aug 30;207(9):1923-38
Authors: Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam LA, Chrzanowska-Wodnicka M, White… . . . → Read More: Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.

Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums.

Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums.
J Exp Med. 2010 Aug 30;207(9):1807-17
Authors: Ravichandran KS
Everyday we turnover billions of cells. The quick, efficient, and immuno… . . . → Read More: Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums.

Sliding set-points of immune responses for therapy of autoimmunity.

Sliding set-points of immune responses for therapy of autoimmunity.
J Exp Med. 2010 Aug 30;207(9):1819-23
Authors: Hsieh CS, Bautista JL
Although recent developments in the treatment of autoimmune disease have dramat… . . . → Read More: Sliding set-points of immune responses for therapy of autoimmunity.

The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3.

The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3.
Nat Immunol. 2010 Aug;11(8):743-50
Authors: Kim H, Seed B
Viral infection induc… . . . → Read More: The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3.

Antimicrobial activity of mucosal-associated invariant T cells.

Antimicrobial activity of mucosal-associated invariant T cells.
Nat Immunol. 2010 Aug;11(8):701-8
Authors: Le Bourhis L, Martin E, Péguillet I, Guihot A, Froux N, Coré M, Lévy E, Dusseaux M, Meyssonnier V, Premel V… . . . → Read More: Antimicrobial activity of mucosal-associated invariant T cells.

T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells.

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T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells.
Nat Immunol. 2010 Aug;11(8):709-16
Authors: Weinreich MA, Odumade OA, Jameson SC, Hogquist KA
Se… . . . → Read More: T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells.

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.

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Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.
Nat Immunol. 2010 Aug;11(8):751-8
Authors: Divangahi M, Desjardins D, Nunes-Alves C, Remold HG, Behar SM
The fate of infe… . . . → Read More: Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis.

N-linked glycosylation selectively regulates autonomous precursor BCR function.

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N-linked glycosylation selectively regulates autonomous precursor BCR function.
Nat Immunol. 2010 Aug;11(8):759-65
Authors: Ubelhart R, Bach MP, Eschbach C, Wossning T, Reth M, Jumaa H
Developing B c… . . . → Read More: N-linked glycosylation selectively regulates autonomous precursor BCR function.

Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.

Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.
Nat Immunol. 2010 Aug;11(8):717-24
Authors: Hodson DJ, Janas ML, Galloway A, Bell SE, Andrews S, L… . . . → Read More: Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b.

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b.
Nat Immunol. 2010 Aug;11(8):734-42
Authors: Han C, Jin J, Xu S, Liu H, Li N, … . . . → Read More: Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b.

Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression.

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Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression.
Nat Immunol. 2010 Aug;11(8):725-33
Authors: Glasmacher E, Hoefig KP, Vogel… . . . → Read More: Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression.

Elements of a good decision.

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Elements of a good decision.
Nat Immunol. 2010 Aug;11(8):645
Authors:
Signal integration, network complexities and genetic programming render the immune system ready to react to challenges from witho… . . . → Read More: Elements of a good decision.

Programming dendritic cells to induce T(H)2 and tolerogenic responses.

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Programming dendritic cells to induce T(H)2 and tolerogenic responses.
Nat Immunol. 2010 Aug;11(8):647-55
Authors: Pulendran B, Tang H, Manicassamy S
A fundamental puzzle in immunology is how the imm… . . . → Read More: Programming dendritic cells to induce T(H)2 and tolerogenic responses.

Epithelial decision makers: in search of the ‘epimmunome’.

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Epithelial decision makers: in search of the ‘epimmunome’.
Nat Immunol. 2010 Aug;11(8):656-65
Authors: Swamy M, Jamora C, Havran W, Hayday A
Frequent microbial and nonmicrobial challenges to epitheli… . . . → Read More: Epithelial decision makers: in search of the ‘epimmunome’.

Decision checkpoints in the thymus.

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Decision checkpoints in the thymus.
Nat Immunol. 2010 Aug;11(8):666-73
Authors: Carpenter AC, Bosselut R
The development of T cells in the thymus involves several differentiation and proliferation ev… . . . → Read More: Decision checkpoints in the thymus.

Effector T cell plasticity: flexibility in the face of changing circumstances.

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Effector T cell plasticity: flexibility in the face of changing circumstances.
Nat Immunol. 2010 Aug;11(8):674-80
Authors: Murphy KM, Stockinger B
As more states of CD4 T cell differentiation are unc… . . . → Read More: Effector T cell plasticity: flexibility in the face of changing circumstances.

Control systems and decision making for antibody production.

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Control systems and decision making for antibody production.
Nat Immunol. 2010 Aug;11(8):681-8
Authors: Goodnow CC, Vinuesa CG, Randall KL, Mackay F, Brink R
This paper synthesizes recent progress to… . . . → Read More: Control systems and decision making for antibody production.

Integrins limit the Toll.

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Integrins limit the Toll.
Nat Immunol. 2010 Aug;11(8):691-3
Authors: Means TK, Luster AD

PMID: 20644576 [PubMed - indexed for MEDLINE]
. . . → Read More: Integrins limit the Toll.

Fighting infection with your MAITs.

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Fighting infection with your MAITs.
Nat Immunol. 2010 Aug;11(8):693-5
Authors: Godfrey DI, Rossjohn J, McCluskey J

PMID: 20644577 [PubMed - indexed for MEDLINE]
. . . → Read More: Fighting infection with your MAITs.

MafB as a type I interferon rheostat.

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MafB as a type I interferon rheostat.
Nat Immunol. 2010 Aug;11(8):695-6
Authors: Motohashi H, Igarashi K

PMID: 20644578 [PubMed - indexed for MEDLINE]
. . . → Read More: MafB as a type I interferon rheostat.

RNA-binding proteins come out of the shadows.

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RNA-binding proteins come out of the shadows.
Nat Immunol. 2010 Aug;11(8):697-8
Authors: Nedjic J, Aifantis I

PMID: 20644579 [PubMed - indexed for MEDLINE]
. . . → Read More: RNA-binding proteins come out of the shadows.

Expression and function of CD300 in NK cells.

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Expression and function of CD300 in NK cells.
J Immunol. 2010 Sep 1;185(5):2877-86
Authors: Lankry D, Simic H, Klieger Y, Levi-Schaffer F, Jonjic S, Mandelboim O
The killing activity of NK cells is r… . . . → Read More: Expression and function of CD300 in NK cells.

Nonredundant roles for leukotriene B(4) receptors BLT1 and BLT2 in inflammatory arthritis.

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Nonredundant roles for leukotriene B(4) receptors BLT1 and BLT2 in inflammatory arthritis.
J Immunol. 2010 Sep 1;185(5):3049-56
Authors: Mathis SP, Jala VR, Lee DM, Haribabu B
Lipid mediators derived… . . . → Read More: Nonredundant roles for leukotriene B(4) receptors BLT1 and BLT2 in inflammatory arthritis.

Regulation of virus-specific CD4(+) T cell function by multiple costimulatory receptors during chronic HIV infection.

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Regulation of virus-specific CD4(+) T cell function by multiple costimulatory receptors during chronic HIV infection.
J Immunol. 2010 Sep 1;185(5):3007-18
Authors: Kassu A, Marcus RA, D’Souza MB, Kelly-McKni… . . . → Read More: Regulation of virus-specific CD4(+) T cell function by multiple costimulatory receptors during chronic HIV infection.

Peripheral blood B cell subset skewing is associated with altered cell cycling and intrinsic resistance to apoptosis and reflects a state of immune activation in chronic hepatitis C virus infection.

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Peripheral blood B cell subset skewing is associated with altered cell cycling and intrinsic resistance to apoptosis and reflects a state of immune activation in chronic hepatitis C virus infection.
J Immunol. 2010 S… . . . → Read More: Peripheral blood B cell subset skewing is associated with altered cell cycling and intrinsic resistance to apoptosis and reflects a state of immune activation in chronic hepatitis C virus infection.

The migration of T cells in response to influenza virus is altered in neonatal mice.

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The migration of T cells in response to influenza virus is altered in neonatal mice.
J Immunol. 2010 Sep 1;185(5):2980-8
Authors: Lines JL, Hoskins S, Hollifield M, Cauley LS, Garvy BA
Influenza viru… . . . → Read More: The migration of T cells in response to influenza virus is altered in neonatal mice.

Trpm4 differentially regulates Th1 and th2 function by altering calcium signaling and NFAT localization.

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Trpm4 differentially regulates Th1 and th2 function by altering calcium signaling and NFAT localization.
J Immunol. 2010 Sep 1;185(5):2836-46
Authors: Weber KS, Hildner K, Murphy KM, Allen PM
Th cell… . . . → Read More: Trpm4 differentially regulates Th1 and th2 function by altering calcium signaling and NFAT localization.

Thymic stromal lymphopoietin in cigarette smoke-exposed human airway smooth muscle.

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Thymic stromal lymphopoietin in cigarette smoke-exposed human airway smooth muscle.
J Immunol. 2010 Sep 1;185(5):3035-40
Authors: Smelter DF, Sathish V, Thompson MA, Pabelick CM, Vassallo R, Prakash YS
. . . → Read More: Thymic stromal lymphopoietin in cigarette smoke-exposed human airway smooth muscle.

Distinct cell death programs in monocytes regulate innate responses following challenge with common causes of invasive bacterial disease.

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Distinct cell death programs in monocytes regulate innate responses following challenge with common causes of invasive bacterial disease.
J Immunol. 2010 Sep 1;185(5):2968-79
Authors: Webster SJ, Daigneault … . . . → Read More: Distinct cell death programs in monocytes regulate innate responses following challenge with common causes of invasive bacterial disease.

TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis.

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TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis.
J Immunol. 2010 Sep 1;185(5):2989-97
Authors: Demento SL, Bonafé N, Cui W, Kaech SM, Caplan MJ, Fi… . . . → Read More: TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis.

Soluble HIV Tat protein removes the IL-7 receptor alpha-chain from the surface of resting CD8 T cells and targets it for degradation.

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Soluble HIV Tat protein removes the IL-7 receptor alpha-chain from the surface of resting CD8 T cells and targets it for degradation.
J Immunol. 2010 Sep 1;185(5):2854-66
Authors: Faller EM, Sugden SM, McVey… . . . → Read More: Soluble HIV Tat protein removes the IL-7 receptor alpha-chain from the surface of resting CD8 T cells and targets it for degradation.

TLR-mediated loss of CD62L focuses B cell traffic to the spleen during Salmonella typhimurium infection.

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TLR-mediated loss of CD62L focuses B cell traffic to the spleen during Salmonella typhimurium infection.
J Immunol. 2010 Sep 1;185(5):2737-46
Authors: Morrison VL, Barr TA, Brown S, Gray D
B cells re… . . . → Read More: TLR-mediated loss of CD62L focuses B cell traffic to the spleen during Salmonella typhimurium infection.

Cryptic epitopes induce high-titer humoral immune response in patients with cancer.

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Cryptic epitopes induce high-titer humoral immune response in patients with cancer.
J Immunol. 2010 Sep 1;185(5):3095-102
Authors: Fischer E, Kobold S, Kleber S, Kubuschok B, Braziulis E, Knuth A, Renner C, … . . . → Read More: Cryptic epitopes induce high-titer humoral immune response in patients with cancer.

Direct presentation regulates the magnitude of the CD8(+) T cell response to cell-associated antigen through prolonged T cell proliferation.

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Direct presentation regulates the magnitude of the CD8(+) T cell response to cell-associated antigen through prolonged T cell proliferation.
J Immunol. 2010 Sep 1;185(5):2763-72
Authors: Tatum AM, Watson AM,… . . . → Read More: Direct presentation regulates the magnitude of the CD8(+) T cell response to cell-associated antigen through prolonged T cell proliferation.

B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses.

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B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses.
J Immunol. 2010 Sep 1;185(5):2730-6
Authors: Kashiwakuma D, Suto A, Hiramatsu Y, Ik… . . . → Read More: B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses.

Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alphabeta T cell receptors.

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Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alphabeta T cell receptors.
J Immunol. 2010 Sep 1;185(5):2951-9
Authors: Kim ST, Touma M, Takeuchi K, Sun ZY, Dave… . . . → Read More: Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alphabeta T cell receptors.

Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency.

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Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency.
J Immunol. 2010 Sep 1;185(5):2721-9
Authors: Wingender G, Krebs P, Beutler B, Kr… . . . → Read More: Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency.

Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairment.

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Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairment.
J Immunol. 2010 Sep 1;185(5):2867-76
Authors: Potula R, Hawkins BJ, Cenna JM, Fan S, Dykstra H,… . . . → Read More: Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairment.

Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation.

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Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation.
J Immunol. 2010 Sep 1;185(5):3076-85
Authors: Naura AS, Zerfaoui M, Kim H, Abd El… . . . → Read More: Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation.

Essential role of endogenous heat shock protein 90 of dendritic cells in antigen cross-presentation.

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Essential role of endogenous heat shock protein 90 of dendritic cells in antigen cross-presentation.
J Immunol. 2010 Sep 1;185(5):2693-700
Authors: Ichiyanagi T, Imai T, Kajiwara C, Mizukami S, Nakai A, Naka… . . . → Read More: Essential role of endogenous heat shock protein 90 of dendritic cells in antigen cross-presentation.

Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.

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Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.
J Immunol. 2010 Sep 1;185(5):2819-27
Authors: Cannons JL, Wu JZ, Gomez-Rodriguez J, Zhang J, Dong B, Liu Y, S… . . . → Read More: Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.

Long-term human CD34(+) stem cell-engrafted nonobese diabetic/SCID/IL-2Rgamma(null) mice show impaired CD8(+) T cell maintenance and a functional arrest of immature NK cells.

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Long-term human CD34(+) stem cell-engrafted nonobese diabetic/SCID/IL-2Rgamma(null) mice show impaired CD8(+) T cell maintenance and a functional arrest of immature NK cells.
J Immunol. 2010 Sep 1;185(5):2710-20
. . . → Read More: Long-term human CD34(+) stem cell-engrafted nonobese diabetic/SCID/IL-2Rgamma(null) mice show impaired CD8(+) T cell maintenance and a functional arrest of immature NK cells.

Fc receptor-like A associates with intracellular IgG and IgM but is dispensable for antigen-specific immune responses.

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Fc receptor-like A associates with intracellular IgG and IgM but is dispensable for antigen-specific immune responses.
J Immunol. 2010 Sep 1;185(5):2960-7
Authors: Wilson TJ, Gilfillan S, Colonna M
F… . . . → Read More: Fc receptor-like A associates with intracellular IgG and IgM but is dispensable for antigen-specific immune responses.

Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes.

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Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes.
J Immunol. 2010 Sep 1;185(5):3028-34
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GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1.

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GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1.
J Immunol. 2010 Sep 1;185(5):2828-35
Authors: Rausch MP, Irvine KR, Antony PA, Restifo NP, Cresswell P, Hastings KT
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B1 cells promote pancreas infiltration by autoreactive T cells.

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B1 cells promote pancreas infiltration by autoreactive T cells.
J Immunol. 2010 Sep 1;185(5):2800-7
Authors: Ryan GA, Wang CJ, Chamberlain JL, Attridge K, Schmidt EM, Kenefeck R, Clough LE, Dunussi-Joannopou… . . . → Read More: B1 cells promote pancreas infiltration by autoreactive T cells.

Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: generation and analysis of a novel null mutation in mice.

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Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: generation and analysis of a novel null mutation in mice.
J Immunol. 2010 Sep 1;185(5):3064-75
Authors: Németh T, Futosi K, Habl… . . . → Read More: Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: generation and analysis of a novel null mutation in mice.

Roles for TGF-beta and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice.

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Roles for TGF-beta and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice.
J Immunol. 2010 Sep 1;185(5):2754-62
Authors: Burton OT, … . . . → Read More: Roles for TGF-beta and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice.

Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.

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Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.
J Immunol. 2010 Sep 1;185(5):2918-26
Authors: Gross CC, Brzostowski JA,… . . . → Read More: Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.

ERK is integral to the IFN-gamma-mediated activation of STAT1, the expression of key genes implicated in atherosclerosis, and the uptake of modified lipoproteins by human macrophages.

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ERK is integral to the IFN-gamma-mediated activation of STAT1, the expression of key genes implicated in atherosclerosis, and the uptake of modified lipoproteins by human macrophages.
J Immunol. 2010 Sep 1;185(5):304… . . . → Read More: ERK is integral to the IFN-gamma-mediated activation of STAT1, the expression of key genes implicated in atherosclerosis, and the uptake of modified lipoproteins by human macrophages.

Tumor cell-released TLR4 ligands stimulate Gr-1(+)CD11b(+)F4/80(+) cells to induce apoptosis of activated T cells.

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Tumor cell-released TLR4 ligands stimulate Gr-1(+)CD11b(+)F4/80(+) cells to induce apoptosis of activated T cells.
J Immunol. 2010 Sep 1;185(5):2773-82
Authors: Liu YY, Sun LC, Wei JJ, Li D, Yuan Y, Yan B, L… . . . → Read More: Tumor cell-released TLR4 ligands stimulate Gr-1(+)CD11b(+)F4/80(+) cells to induce apoptosis of activated T cells.

Escherichia coli K1 promotes the ligation of CD47 with thrombospondin-1 to prevent the maturation of dendritic cells in the pathogenesis of neonatal meningitis.

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Escherichia coli K1 promotes the ligation of CD47 with thrombospondin-1 to prevent the maturation of dendritic cells in the pathogenesis of neonatal meningitis.
J Immunol. 2010 Sep 1;185(5):2998-3006
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TLR and B cell receptor signals to B cells differentially program primary and memory Th1 responses to Salmonella enterica.

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TLR and B cell receptor signals to B cells differentially program primary and memory Th1 responses to Salmonella enterica.
J Immunol. 2010 Sep 1;185(5):2783-9
Authors: Barr TA, Brown S, Mastroeni P, Gray D
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Intralesional delivery of dendritic cells engineered to express T-bet promotes protective type 1 immunity and the normalization of the tumor microenvironment.

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Intralesional delivery of dendritic cells engineered to express T-bet promotes protective type 1 immunity and the normalization of the tumor microenvironment.
J Immunol. 2010 Sep 1;185(5):2895-902
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Mast cells contribute to the mucosal adjuvant effect of CTA1-DD after IgG-complex formation.

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Mast cells contribute to the mucosal adjuvant effect of CTA1-DD after IgG-complex formation.
J Immunol. 2010 Sep 1;185(5):2935-41
Authors: Fang Y, Larsson L, Mattsson J, Lycke N, Xiang Z
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The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.

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The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.
J Immunol. 2010 Sep 1;185(5):3086-94
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NK cells as effectors of acquired immune responses: effector CD4(+) T cell-dependent activation of NK cells following vaccination.

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NK cells as effectors of acquired immune responses: effector CD4(+) T cell-dependent activation of NK cells following vaccination.
J Immunol. 2010 Sep 1;185(5):2808-18
Authors: Horowitz A, Behrens RH, Okell … . . . → Read More: NK cells as effectors of acquired immune responses: effector CD4(+) T cell-dependent activation of NK cells following vaccination.

Neutrophils influence the level of antigen presentation during the immune response to protein antigens in adjuvants.

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Neutrophils influence the level of antigen presentation during the immune response to protein antigens in adjuvants.
J Immunol. 2010 Sep 1;185(5):2927-34
Authors: Yang CW, Strong BS, Miller MJ, Unanue ER
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Activation of the ancestral polarity regulator protein kinase Czeta at the immunological synapse drives polarization of Th cell secretory machinery toward APCs.

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Activation of the ancestral polarity regulator protein kinase Czeta at the immunological synapse drives polarization of Th cell secretory machinery toward APCs.
J Immunol. 2010 Sep 1;185(5):2887-94
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Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence.

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Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence.
J Immunol. 2010 Sep 1;185(5):2670-4
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Dendritic cell modification of neutrophil responses to infection after burn injury.

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Dendritic cell modification of neutrophil responses to infection after burn injury.
J Immunol. 2010 Sep 1;185(5):2847-53
Authors: Bohannon J, Cui W, Sherwood E, Toliver-Kinsky T
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Cutting edge: all-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu.

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Cutting edge: all-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu.
J Immunol. 2010 Sep 1;185(5):2675-9
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A proinflammatory role for proteolytically cleaved annexin A1 in neutrophil transendothelial migration.

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A proinflammatory role for proteolytically cleaved annexin A1 in neutrophil transendothelial migration.
J Immunol. 2010 Sep 1;185(5):3057-63
Authors: Williams SL, Milne IR, Bagley CJ, Gamble JR, Vadas MA, Pi… . . . → Read More: A proinflammatory role for proteolytically cleaved annexin A1 in neutrophil transendothelial migration.

Ral isoforms are implicated in FcgammaR-mediated phagocytosis: activation of phospholipase D by RalA.

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Ral isoforms are implicated in FcgammaR-mediated phagocytosis: activation of phospholipase D by RalA.
J Immunol. 2010 Sep 1;185(5):2942-50
Authors: Corrotte M, Nyguyen AP, Harlay ML, Vitale N, Bader MF, Gran… . . . → Read More: Ral isoforms are implicated in FcgammaR-mediated phagocytosis: activation of phospholipase D by RalA.

Dendritic cells induce regulatory T cell proliferation through antigen-dependent and -independent interactions.

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Dendritic cells induce regulatory T cell proliferation through antigen-dependent and -independent interactions.
J Immunol. 2010 Sep 1;185(5):2790-9
Authors: Zou T, Caton AJ, Koretzky GA, Kambayashi T
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Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.

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Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.
J Immunol. 2010 Sep 1;185(5):2903-17
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B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses.

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B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses.
J Immunol. 2010 Sep 1;185(5):2747-53
Authors: Lin PY, Sun L, Thibodeaux SR, Ludwig SM, Vadlamudi RK, Hurez VJ, Bahar R, … . . . → Read More: B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses.

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

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Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.
J Immunol. 2010 Sep 1;185(5):2701-9
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Reciprocal functional modulation of the activation of T lymphocytes and fibroblasts derived from human solid tumors.

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Reciprocal functional modulation of the activation of T lymphocytes and fibroblasts derived from human solid tumors.
J Immunol. 2010 Sep 1;185(5):2681-92
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