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Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells.

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Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells.
Immunity. 2010 Aug 27;33(2):192-202
Authors: Staudt V, Bothur E, Klein M, Lingnau K, Reuter S, Grebe N, Gerlitzk… . . . → Read More: Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells.

SAP Protein-Dependent Natural Killer T-like Cells Regulate the Development of CD8(+) T Cells with Innate Lymphocyte Characteristics.

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SAP Protein-Dependent Natural Killer T-like Cells Regulate the Development of CD8(+) T Cells with Innate Lymphocyte Characteristics.
Immunity. 2010 Aug 27;33(2):203-215
Authors: Verykokakis M, Boos MD, Bende… . . . → Read More: SAP Protein-Dependent Natural Killer T-like Cells Regulate the Development of CD8(+) T Cells with Innate Lymphocyte Characteristics.

Follicular B Cell Trafficking within the Spleen Actively Restricts Humoral Immune Responses.

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Follicular B Cell Trafficking within the Spleen Actively Restricts Humoral Immune Responses.
Immunity. 2010 Aug 27;33(2):254-265
Authors: Hoek KL, Gordy LE, Collins PL, Parekh VV, Aune TM, Joyce S, Thomas JW… . . . → Read More: Follicular B Cell Trafficking within the Spleen Actively Restricts Humoral Immune Responses.

Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling.

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Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling.
Immunity. 2010 Aug 27;33(2):241-253
Authors: Deenick EK, Chan A, Ma CS, Gatto… . . . → Read More: Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling.

The Ubiquitin Modifying Enzyme A20 Restricts B Cell Survival and Prevents Autoimmunity.

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The Ubiquitin Modifying Enzyme A20 Restricts B Cell Survival and Prevents Autoimmunity.
Immunity. 2010 Aug 27;33(2):181-191
Authors: Tavares RM, Turer EE, Liu CL, Advincula R, Scapini P, Rhee L, Barrera J, Lo… . . . → Read More: The Ubiquitin Modifying Enzyme A20 Restricts B Cell Survival and Prevents Autoimmunity.

Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis.

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Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis.
Immunity. 2010 Aug 27;33(2):266-278
Authors: Chou RC, Kim ND, Sadik CD, Seung E, Lan Y, Byrne MH, Ha… . . . → Read More: Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis.

TCF-1 Flips the Switch on Eomes.

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TCF-1 Flips the Switch on Eomes.
Immunity. 2010 Aug 27;33(2):145-147
Authors: Paley MA, Wherry EJ
The interaction between different transcriptional pathways in CD8(+) T cell memory remains incompletel… . . . → Read More: TCF-1 Flips the Switch on Eomes.

Chemokines: Sirens of Neutrophil Recruitment-but Is It Just One Song?

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Chemokines: Sirens of Neutrophil Recruitment-but Is It Just One Song?
Immunity. 2010 Aug 27;33(2):148-149
Authors: McDonald B, Kubes P
Neutrophil trafficking to inflamed tissues requires the integrati… . . . → Read More: Chemokines: Sirens of Neutrophil Recruitment-but Is It Just One Song?

Differentiation and Persistence of Memory CD8(+) T Cells Depend on T Cell Factor 1.

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Differentiation and Persistence of Memory CD8(+) T Cells Depend on T Cell Factor 1.
Immunity. 2010 Aug 27;33(2):229-240
Authors: Zhou X, Yu S, Zhao DM, Harty JT, Badovinac VP, Xue HH
T cell factor 1 (… . . . → Read More: Differentiation and Persistence of Memory CD8(+) T Cells Depend on T Cell Factor 1.

Checks and Balances: IL-23 in the Intestine.

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Checks and Balances: IL-23 in the Intestine.
Immunity. 2010 Aug 27;33(2):150-152
Authors: Huber S, Flavell RA
In this issue of Immunity, Ahern et al. (2010) show that IL-23R signaling in CD4(+) T cell… . . . → Read More: Checks and Balances: IL-23 in the Intestine.

Lysosomal alpha-Galactosidase Controls the Generation of Self Lipid Antigens for Natural Killer T Cells.

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Lysosomal alpha-Galactosidase Controls the Generation of Self Lipid Antigens for Natural Killer T Cells.
Immunity. 2010 Aug 27;33(2):216-228
Authors: Darmoise A, Teneberg S, Bouzonville L, Brady RO, Beck M, K… . . . → Read More: Lysosomal alpha-Galactosidase Controls the Generation of Self Lipid Antigens for Natural Killer T Cells.

The Phosphatase PTP-PEST Promotes Secondary T Cell Responses by Dephosphorylating the Protein Tyrosine Kinase Pyk2.

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The Phosphatase PTP-PEST Promotes Secondary T Cell Responses by Dephosphorylating the Protein Tyrosine Kinase Pyk2.
Immunity. 2010 Aug 27;33(2):167-180
Authors: Davidson D, Shi X, Zhong MC, Rhee I, Veillette … . . . → Read More: The Phosphatase PTP-PEST Promotes Secondary T Cell Responses by Dephosphorylating the Protein Tyrosine Kinase Pyk2.

Interferon Regulatory Factor 4: Combinational Control of Lymphocyte Differentiation.

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Interferon Regulatory Factor 4: Combinational Control of Lymphocyte Differentiation.
Immunity. 2010 Aug 27;33(2):141-143
Authors: Veldhoen M
Transcriptional mechanisms involved in the differentiation … . . . → Read More: Interferon Regulatory Factor 4: Combinational Control of Lymphocyte Differentiation.

The Hunt for iNKT Cell Antigens: alpha-Galactosidase-Deficient Mice to the Rescue?

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The Hunt for iNKT Cell Antigens: alpha-Galactosidase-Deficient Mice to the Rescue?
Immunity. 2010 Aug 27;33(2):143-145
Authors: Van Kaer L, Joyce S
The endogenous lipids that control the functions of … . . . → Read More: The Hunt for iNKT Cell Antigens: alpha-Galactosidase-Deficient Mice to the Rescue?

Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity.

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Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity.
Immunity. 2010 Aug 27;33(2):153-165
Authors: Malek TR, Castro I
Interleukin-2 receptor (IL-2R) signaling regulates to… . . . → Read More: Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity.

Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells.

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Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells.
Immunity. 2010 Aug 27;33(2):279-288
Authors: Ahern PP, Schiering C, Buonocore S, McGeachy MJ, Cua DJ, Maloy KJ, Powrie F
. . . → Read More: Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells.