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By Schaefer A, Im HI, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny PJ, O'Carroll D, Greengard P, on September 2nd, 2010
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Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.
J Exp Med. 2010 Aug 30;207(9):1843-51
Authors: Schaefer A, Im HI, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny P… . . . → Read More: Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.
By Sundling C, Forsell MN, O'Dell S, Feng Y, Chakrabarti B, Rao SS, Loré K, Mascola JR, Wyatt RT, Douagi I, Karlsson Hedestam GB, on September 2nd, 2010
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Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.
J Exp Med. 2010 Aug 30;207(9):2003-17
Authors: Sundling C, Forsell MN, O’Dell S, Feng Y, Chakrabarti B… . . . → Read More: Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.
By Grinberg-Bleyer Y, Baeyens A, You S, Elhage R, Fourcade G, Gregoire S, Cagnard N, Carpentier W, Tang Q, Bluestone J, Chatenoud L, Klatzmann D, Salomon BL, Piaggio E, on September 2nd, 2010
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IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells.
J Exp Med. 2010 Aug 30;207(9):1871-8
Authors: Grinberg-Bleyer Y, Baeyens A, You S, Elhage R, Fourcade… . . . → Read More: IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells.
By Pietzsch J, Scheid JF, Mouquet H, Klein F, Seaman MS, Jankovic M, Corti D, Lanzavecchia A, Nussenzweig MC, on September 2nd, 2010
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Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness.
J Exp Med. 2010 Aug 30;207(9):1995-2002
Authors: Pietzsch J, Scheid JF, Mouquet H, Klein F, Seaman MS… . . . → Read More: Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness.
By Nishio J, Feuerer M, Wong J, Mathis D, Benoist C, on September 2nd, 2010
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Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints.
J Exp Med. 2010 Aug 30;207(9):1879-89
Authors: Nishio J, Feuerer M, Wong J, Mathis D, Benoist C… . . . → Read More: Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints.
By Irla M, Küpfer N, Suter T, Lissilaa R, Benkhoucha M, Skupsky J, Lalive PH, Fontana A, Reith W, Hugues S, on September 2nd, 2010
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MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity.
J Exp Med. 2010 Aug 30;207(9):1891-905
Authors: Irla M, Küpfer N, Suter T, Lissilaa R, B… . . . → Read More: MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity.
By Hao J, Liu R, Piao W, Zhou Q, Vollmer TL, Campagnolo DI, Xiang R, La Cava A, Van Kaer L, Shi FD, on September 2nd, 2010
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Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology.
J Exp Med. 2010 Aug 30;207(9):1907-21
Authors: Hao J, Liu R, Piao W, Zhou Q, Vollmer TL, Campa… . . . → Read More: Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology.
By Shih HY, Krangel MS, on September 2nd, 2010
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Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.
J Exp Med. 2010 Aug 30;207(9):1835-41
Authors: Shih HY, Krangel MS
Studies have suggested that antigen rec… . . . → Read More: Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.
By Markowska AI, Liu FT, Panjwani N, on September 2nd, 2010
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Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response.
J Exp Med. 2010 Aug 30;207(9):1981-93
Authors: Markowska AI, Liu FT, Panjwani N
Recent studies have shown that a ca… . . . → Read More: Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response.
By Falet H, Pollitt AY, Begonja AJ, Weber SE, Duerschmied D, Wagner DD, Watson SP, Hartwig JH, on September 2nd, 2010
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A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function.
J Exp Med. 2010 Aug 30;207(9):1967-79
Authors: Falet H, Pollitt AY, Begonja AJ, Weber SE, Duerschmie… . . . → Read More: A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function.
By Park B, Spooner E, Houser BL, Strominger JL, Ploegh HL, on September 2nd, 2010
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The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation.
J Exp Med. 2010 Aug 30;207(9):2033-41
Authors: Park B, Spooner E, Houser BL, Strominger JL, Ploegh HL
Human cytomegalovi… . . . → Read More: The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation.
By Kim HK, Cheng AG, Kim HY, Missiakas DM, Schneewind O, on September 2nd, 2010
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Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice.
J Exp Med. 2010 Aug 30;207(9):1863-70
Authors: Kim HK, Cheng AG, Kim HY, Missiakas DM, Schneewind O
… . . . → Read More: Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice.
By Fafi-Kremer S, Fofana I, Soulier E, Carolla P, Meuleman P, Leroux-Roels G, Patel AH, Cosset FL, Pessaux P, Doffoël M, Wolf P, Stoll-Keller F, Baumert TF, on September 2nd, 2010
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Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation.
J Exp Med. 2010 Aug 30;207(9):2019-31
Authors: Fafi-Kremer S, Fofana I, Soulier … . . . → Read More: Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation.
By Zhou J, Tang PC, Qin L, Gayed PM, Li W, Skokos EA, Kyriakides TR, Pober JS, Tellides G, on September 2nd, 2010
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CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses.
J Exp Med. 2010 Aug 30;207(9):1951-66
Authors: Zhou J, Tang P… . . . → Read More: CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses.
By Campbell L, Emmerson E, Davies F, Gilliver SC, Krust A, Chambon P, Ashcroft GS, Hardman MJ, on September 2nd, 2010
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Estrogen promotes cutaneous wound healing via estrogen receptor {beta} independent of its antiinflammatory activities.
J Exp Med. 2010 Aug 30;207(9):1825-33
Authors: Campbell L, Emmerson E, Davies F, Gillive… . . . → Read More: Estrogen promotes cutaneous wound healing via estrogen receptor {beta} independent of its antiinflammatory activities.
By Li P, Li M, Lindberg MR, Kennett MJ, Xiong N, Wang Y, on September 2nd, 2010
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PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.
J Exp Med. 2010 Aug 30;207(9):1853-62
Authors: Li P, Li M, Lindberg MR, Kennett MJ, Xiong N, Wang Y
Neu… . . . → Read More: PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.
By Lai AY, Fatemi M, Dhasarathy A, Malone C, Sobol SE, Geigerman C, Jaye DL, Mav D, Shah R, Li L, Wade PA, on September 2nd, 2010
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DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.
J Exp Med. 2010 Aug 30;207(9):1939-50
Authors: Lai AY, Fatemi M, Dhasarathy A, Malone C, Sobol SE, Geigerman C, Jaye… . . . → Read More: DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.
By Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam LA, Chrzanowska-Wodnicka M, White GC, Malarkannan S, on September 2nd, 2010
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Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.
J Exp Med. 2010 Aug 30;207(9):1923-38
Authors: Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam LA, Chrzanowska-Wodnicka M, White… . . . → Read More: Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.
By Ravichandran KS, on September 2nd, 2010
Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums.
J Exp Med. 2010 Aug 30;207(9):1807-17
Authors: Ravichandran KS
Everyday we turnover billions of cells. The quick, efficient, and immuno… . . . → Read More: Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums.
By Hsieh CS, Bautista JL, on September 2nd, 2010
Sliding set-points of immune responses for therapy of autoimmunity.
J Exp Med. 2010 Aug 30;207(9):1819-23
Authors: Hsieh CS, Bautista JL
Although recent developments in the treatment of autoimmune disease have dramat… . . . → Read More: Sliding set-points of immune responses for therapy of autoimmunity.
By Rasmussen KD, Simmini S, Abreu-Goodger C, Bartonicek N, Di Giacomo M, Bilbao-Cortes D, Horos R, Von Lindern M, Enright AJ, O'Carroll D, on August 3rd, 2010
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The miR-144/451 locus is required for erythroid homeostasis.
J Exp Med. 2010 Jul 5;207(7):1351-8
Authors: Rasmussen KD, Simmini S, Abreu-Goodger C, Bartonicek N, Di Giacomo M, Bilbao-Cortes D, Horos R, Von L… . . . → Read More: The miR-144/451 locus is required for erythroid homeostasis.
By Lu P, Hankel IL, Knisz J, Marquardt A, Chiang MY, Grosse J, Constien R, Meyer T, Schroeder A, Zeitlmann L, Al-Alem U, Friedman AD, Elliott EI, Meyerholz DK, Waldschmidt TJ, Rothman PB, Colgan JD, on August 3rd, 2010
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The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.
J Exp Med. 2010 Jul 5;207(7):1359-67
Authors: Lu P, Hankel IL, Knisz J, Marquardt A, Chiang MY, Grosse J, Constien R, … . . . → Read More: The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.
By Sander LE, Sackett SD, Dierssen U, Beraza N, Linke RP, Müller M, Blander JM, Tacke F, Trautwein C, on August 3rd, 2010
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Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function.
J Exp Med. 2010 Jul 5;207(7):1453-64
Authors: Sander LE, Sackett SD, Diers… . . . → Read More: Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function.
By Vereecke L, Sze M, Guire CM, Rogiers B, Chu Y, Schmidt-Supprian M, Pasparakis M, Beyaert R, van Loo G, on August 3rd, 2010
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Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis.
J Exp Med. 2010 Jul 5;207(7):1513-23
Authors: Vereecke L, Sze M, Guire CM, Rogiers B, Chu Y, … . . . → Read More: Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis.
By Darrah PA, Hegde ST, Patel DT, Lindsay RW, Chen L, Roederer M, Seder RA, on August 3rd, 2010
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IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform.
J Exp Med. 2010 Jul 5;207(7):1421-33
Authors: Darrah PA, Hegde S… . . . → Read More: IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform.
By Yoo JK, Galligan CL, Virtanen C, Fish EN, on August 3rd, 2010
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Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity.
J Exp Med. 2010 Jul 5;207(7):1435-51
Authors: Yoo JK, Galligan CL, Virtanen C, Fish EN
Antiinflu… . . . → Read More: Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity.
By Walter JE, Rucci F, Patrizi L, Recher M, Regenass S, Paganini T, Keszei M, Pessach I, Lang PA, Poliani PL, Giliani S, Al-Herz W, Cowan MJ, Puck JM, Bleesing J, Niehues T, Schuetz C, Malech H, DeRavin SS, Facchetti F, Gennery AR, Andersson E, Kamani N, on August 3rd, 2010
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Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.
J Exp Med. 2010 Jul 5;207(7):1541-54
Authors: Walter JE, Rucci F, Patrizi L, Recher M, Regenass … . . . → Read More: Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.
By Cassani B, Poliani PL, Marrella V, Schena F, Sauer AV, Ravanini M, Strina D, Busse CE, Regenass S, Wardemann H, Martini A, Facchetti F, van der Burg M, Rolink AG, Vezzoni P, Grassi F, Traggiai E, Villa A, on August 3rd, 2010
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Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome.
J Exp Med. 2010 Jul 5;207(7):1525-40
Authors: Cassani B, Poliani PL, Marrella V, Schena F, Saue… . . . → Read More: Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome.
By Shafiani S, Tucker-Heard G, Kariyone A, Takatsu K, Urdahl KB, on August 3rd, 2010
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Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis.
J Exp Med. 2010 Jul 5;207(7):1409-20
Authors: Shafiani S, Tucker-Heard G, Kariyone A, Takatsu… . . . → Read More: Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis.
By Zha S, Bassing CH, Sanda T, Brush JW, Patel H, Goff PH, Murphy MM, Tepsuporn S, Gatti RA, Look AT, Alt FW, on August 3rd, 2010
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ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.
J Exp Med. 2010 Jul 5;207(7):1369-80
Authors: Zha S, Bassing CH, Sanda T, Brush JW, Patel H, Goff PH, Murp… . . . → Read More: ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.
By Yamanishi Y, Kitaura J, Izawa K, Kaitani A, Komeno Y, Nakamura M, Yamazaki S, Enomoto Y, Oki T, Akiba H, Abe T, Komori T, Morikawa Y, Kiyonari H, Takai T, Okumura K, Kitamura T, on August 3rd, 2010
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TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury.
J Exp Med. 2010 Jul 5;207(7):1501-11
Authors: Yamanishi Y, Kitaura J, Izawa K, Kaitani A,… . . . → Read More: TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury.
By Gras S, Chen Z, Miles JJ, Liu YC, Bell MJ, Sullivan LC, Kjer-Nielsen L, Brennan RM, Burrows JM, Neller MA, Khanna R, Purcell AW, Brooks AG, McCluskey J, Rossjohn J, Burrows SR, on August 3rd, 2010
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Allelic polymorphism in the T cell receptor and its impact on immune responses.
J Exp Med. 2010 Jul 5;207(7):1555-67
Authors: Gras S, Chen Z, Miles JJ, Liu YC, Bell MJ, Sullivan LC, Kjer-Nielsen L, Brennan R… . . . → Read More: Allelic polymorphism in the T cell receptor and its impact on immune responses.
By Schallenberg S, Tsai PY, Riewaldt J, Kretschmer K, on August 3rd, 2010
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Identification of an immediate Foxp3(-) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice.
J Exp Med. 2010 Jul 5;207(7):1393-407
Authors: Schallenberg S, Tsai PY, … . . . → Read More: Identification of an immediate Foxp3(-) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice.
By Thangada S, Khanna KM, Blaho VA, Oo ML, Im DS, Guo C, Lefrancois L, Hla T, on August 3rd, 2010
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Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics.
J Exp Med. 2010 Jul 5;207(7):1475-83
Authors: Thangada S, Khanna KM, Blaho VA, Oo ML, Im DS,… . . . → Read More: Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics.
By Swanson CL, Wilson TJ, Strauch P, Colonna M, Pelanda R, Torres RM, on August 3rd, 2010
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Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.
J Exp Med. 2010 Jul 5;207(7):1485-500
Authors: Swanson CL, Wilson TJ, Strauch P, Colonna M, Pelanda R, Torres R… . . . → Read More: Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.
By Zhang M, Fennell C, Ranford-Cartwright L, Sakthivel R, Gueirard P, Meister S, Caspi A, Doerig C, Nussenzweig RS, Tuteja R, Sullivan WJ, Roos DS, Fontoura BM, Ménard R, Winzeler EA, Nussenzweig V, on August 3rd, 2010
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The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands.
J Exp Med. 2010 Jul 5;207(7):1465-74
Authors: Zhang M, Fennell C, Ranford-Ca… . . . → Read More: The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands.
By Merkenschlager, M., von Boehmer, H., on August 3rd, 2010
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PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors.
J Exp Med. 2010 Jul 5;207(7):1347-50
Authors: Merkenschlager M, von Boehmer H
Expression of the regulatory T (T reg) cell-a… . . . → Read More: PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors.
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