The Third Reviewer

Lisa Chakrabarti, Rabaab Zahra, Stephen M. Jackson, Parsa Kazemi-Esfarjani, Bryce L. Sopher, Amanda G. Mason, Thomas Toneff, Soyoung Ryu, Scott Shaffer, Janice W. Kansy, Jeremiah Eng, Gennifer Merrihew, Michael J. MacCoss, Anne Murphy, David R. Goodlet… . . . → Read More: Mitochondrial Dysfunction in NnaD Mutant Flies and Purkinje Cell Degeneration Mice Reveals a Role for Nna Proteins in Neuronal Bioenergetics

Josef P. Rauschecker, Amber M. Leaver, Mark Mühlau. Tinnitus, the most common auditory disorder, affects about 40 million people in the United States alone, and its incidence is rising due to an aging population and increasing noise exposure. Altho…. . . . → Read More: Tuning Out the Noise: Limbic-Auditory Interactions in Tinnitus

Tae-Ju Park, Tom Curran. Disabled-1 is a key signaling molecule in the Reelin pathway that plays a critical role in neuronal migration and positioning during brain development. In this issue of Neuron, Yano et al. …. . . . → Read More: Alternative Splicing Disabled by Nova2

Jack Kronengold, Leonard K. Kaczmarek. BK potassium channels regulate spike width and firing rate. A BK point mutation in humans enhances channel activity, leading to epilepsy. In this issue of Neuron, Yang and colleagues use th…. . . . → Read More: A Less Flexible BK Channel Opens More Easily

Verónica Campanucci, Arjun Krishnaswamy, Ellis Cooper. Most people with diabetes develop severe complications of the autonomic nervous system; yet, the underlying causes of many diabetic-induced dysautonomias are poorly understood. Here we explore the… . . . → Read More: Diabetes Depresses Synaptic Transmission in Sympathetic Ganglia by Inactivating nAChRs through a Conserved Intracellular Cysteine Residue

Masato Yano, Yoshika Hayakawa-Yano, Aldo Mele, Robert B. Darnell. Neuronal migration leads to a highly organized laminar structure in the mammalian brain, and its misregulation causes lissencephaly and behavioral and cognitive defects. Reelin signaling… . . . → Read More: Nova2 Regulates Neuronal Migration through an RNA Switch in Disabled-1 Signaling

Qun-Fang Wan, Zhen-Yu Zhou, Pratima Thakur, Alejandro Vila, David M. Sherry, Roger Janz, Ruth Heidelberger. Synaptic vesicle 2 (SV2) proteins, critical for proper nervous system function, are implicated in human epilepsy, yet little is known about thei… . . . → Read More: SV2 Acts via Presynaptic Calcium to Regulate Neurotransmitter Release

Ming-Chia Lee, Ryohei Yasuda, Michael D. Ehlers. Optimal function of neuronal networks requires interplay between rapid forms of Hebbian plasticity and homeostatic mechanisms that adjust the threshold for plasticity, termed metaplasticity. Numer…. . . . → Read More: Metaplasticity at Single Glutamatergic Synapses

Junqiu Yang, Gayathri Krishnamoorthy, Akansha Saxena, Guohui Zhang, Jingyi Shi, Huanghe Yang, Kelli Delaloye, David Sept, Jianmin Cui. Ca2+-activated BK channels modulate neuronal activities, including spike frequency adaptation and synaptic transmissi… . . . → Read More: An Epilepsy/Dyskinesia-Associated Mutation Enhances BK Channel Activation by Potentiating Ca2+ Sensing

Takatoshi Hikida, Kensuke Kimura, Norio Wada, Kazuo Funabiki, Shigetada Nakanishi. In the basal ganglia, convergent input and dopaminergic modulation of the direct striatonigral and the indirect striatopallidal pathways are critical in rewarding and a… . . . → Read More: Distinct Roles of Synaptic Transmission in Direct and Indirect Striatal Pathways to Reward and Aversive Behavior

Agnieszka Krzy?osiak, Monika Szyszka-Niagolov, Marta Wietrzych, Serge Gobaille, Shin-ichi Muramatsu, Wojciech Kr??el. Abnormal signaling by retinoids or n-3 polyunsaturated fatty acids has been implicated in clinical depression. The converging point… . . . → Read More: Retinoid X Receptor Gamma Control of Affective Behaviors Involves Dopaminergic Signaling in Mice

Karim Benchenane, Adrien Peyrache, Mehdi Khamassi, Patrick L. Tierney, Yves Gioanni, Francesco P. Battaglia, Sidney I. Wiener. To study the interplay between hippocampus and medial prefrontal cortex (Pfc) and its importance for learning and memory cons… . . . → Read More: Coherent Theta Oscillations and Reorganization of Spike Timing in the Hippocampal- Prefrontal Network upon Learning

Johannes C. Dahmen, Peter Keating, Fernando R. Nodal, Andreas L. Schulz, Andrew J. King. Sensory systems are known to adapt their coding strategies to the statistics of their environment, but little is still known about the perceptual implications of s… . . . → Read More: Adaptation to Stimulus Statistics in the Perception and Neural Representation of Auditory Space

Uri Nili, Hagar Goldberg, Abraham Weizman, Yadin Dudai. How does the brain encode courage in a real-life fearful situation that demands an immediate response? In this study, volunteers who fear snakes had to bring a live snake into close proximity with… . . . → Read More: Fear Thou Not: Activity of Frontal and Temporal Circuits in Moments of Real-Life Courage

Todor V. Gerdjikov, Caroline G. Bergner, Maik C. Stüttgen, Christian Waiblinger, Cornelius Schwarz. . . . → Read More: Discrimination of Vibrotactile Stimuli in the Rat Whisker System: Behavior and Neurometrics