Structure of the CaMKII?/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

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Peter Rellos, Ashley C. W. Pike, Frank H. Niesen, Eidarus Salah, Wen Hwa Lee, Frank von Delft, Stefan Knapp

Long-term potentiation (LTP), a long-lasting enhancement in communication between neurons, is considered to be the major cellular mechanism underlying learning and memory. LTP triggers high-frequency calcium pulses that result in the activation of . . . → Read More: Structure of the CaMKII?/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

A Novel Role for Dbx1-Derived Cajal-Retzius Cells in Early Regionalization of the Cerebral Cortical Neuroepithelium

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Amélie Griveau, Ugo Borello, Frédéric Causeret, Fadel Tissir, Nicole Boggetto, Sonia Karaz, Alessandra Pierani

Patterning of the cortical neuroepithelium occurs at early stages of embryonic development in response to secreted molecules from signaling centers. These signals have been shown to establish the graded expression of transcription factors in progenitors within the . . . → Read More: A Novel Role for Dbx1-Derived Cajal-Retzius Cells in Early Regionalization of the Cerebral Cortical Neuroepithelium