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By Oldfield, C. S., Marty, A., Stell, B. M., on July 20th, 2010
<p>We demonstrate that single interneurons can toggle the output neurons of the cerebellar cortex (the Purkinje cells) between their two… . . . → Read More: Interneurons of the cerebellar cortex toggle Purkinje cells between up and down states [Neuroscience]
By Monosov, I. E., Sheinberg, D. L., Thompson, K. G., on July 20th, 2010
By Ulusoy, A., Sahin, G., Kirik, D., on July 20th, 2010
<p>Drug-induced dyskinesias in dopamine-denervated animals are known to depend on both pre- and postsynaptic changes of the nigrostriatal circuitry. In… . . . → Read More: Presynaptic dopaminergic compartment determines the susceptibility to L-DOPA-induced dyskinesia in rats [Neuroscience]
By Wang, H.-B., Zhao, B., Zhong, Y.-Q., Li, K.-C., Li, Z.-Y., Wang, Q., Lu, Y.-J., Zhang, Z.-N., He, S.-Q., Zheng, H.-C., Wu, S.-X., Hokfelt, T. G. M., Bao, L., Zhang, X., on July 20th, 2010
Morphine-induced analgesia and antinociceptive tolerance are known to be modulated by interaction between -opioid receptors (DORs) and µ-opioid receptors (MORs)… . . . → Read More: Coexpression of {delta}- and {micro}-opioid receptors in nociceptive sensory neurons [Neuroscience]
By Bedogni, F., Hodge, R. D., Elsen, G. E., Nelson, B. R., Daza, R. A. M., Beyer, R. P., Bammler, T. K., Rubenstein, J. L. R., Hevner, R. F., on July 20th, 2010
<p>Areas and layers of the cerebral cortex are specified by genetic programs that are initiated in progenitor cells and then,… . . . → Read More: Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex [Neuroscience]
By Chen, Y., Rex, C. S., Rice, C. J., Dube, C. M., Gall, C. M., Lynch, G., Baram, T. Z., on July 20th, 2010
<p>Stress affects the hippocampus, a brain region crucial for memory. In rodents, acute stress may reduce density of dendritic spines,… . . . → Read More: Correlated memory defects and hippocampal dendritic spine loss after acute stress involve corticotropin-releasing hormone signaling [Neuroscience]
By Hill, J., Inder, T., Neil, J., Dierker, D., Harwell, J., Van Essen, D., on July 20th, 2010
<p>The cerebral cortex of the human infant at term is complexly folded in a similar fashion to adult cortex but… . . . → Read More: Similar patterns of cortical expansion during human development and evolution [Neuroscience]
By Haramati, S., Chapnik, E., Sztainberg, Y., Eilam, R., Zwang, R., Gershoni, N., McGlinn, E., Heiser, P. W., Wills, A.-M., Wirguin, I., Rubin, L. L., Misawa, H., Tabin, C. J., Brown, R., Chen, A., Hornstein, E., on July 20th, 2010
<p>Defective RNA metabolism is an emerging mechanism involved in ALS pathogenesis and possibly in other neurodegenerative disorders. Here, we show… . . . → Read More: miRNA malfunction causes spinal motor neuron disease [Neuroscience]
By Roffe, M., Beraldo, F. H., Bester, R., Nunziante, M., Bach, C., Mancini, G., Gilch, S., Vorberg, I., Castilho, B. A., Martins, V. R., Hajj, G. N. M., on July 20th, 2010
Transmissible spongiform encephalopathies are fatal neurodegenerative diseases caused by the conversion of prion protein (PrPC) into an infectious isoform (PrPSc)…. . . . → Read More: Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR [Neuroscience]
By Shilyansky, C., Karlsgodt, K. H., Cummings, D. M., Sidiropoulou, K., Hardt, M., James, A. S., Ehninger, D., Bearden, C. E., Poirazi, P., Jentsch, J. D., Cannon, T. D., Levine, M. S., Silva, A. J., on July 20th, 2010
<p>Neurofibromatosis type I (NF1) is one of the most common single-gene causes of learning disabilities. Here, we use behavioral working… . . . → Read More: Neurofibromin regulates corticostriatal inhibitory networks during working memory performance [Neuroscience]
By Proceedings of the National Academy of Sciences current issue, on July 20th, 2010
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