The Third Reviewer

Han-Ki Lee,  Yoosoo Yang,  Zengliu Su,  Changbong Hyeon, Tae-Sun Lee, Hong-Won Lee, Dae-Hyuk Kweon, Yeon-Kyun Shin,  Tae-Young Yoon

In neurons, synaptotagmin 1 (Syt1) is thought to mediate the fusion of synaptic vesicles with the plasma membrane when presynaptic Ca2+ levels rise. However, in vitro reconstitution experiments have failed to recapitulate key characteristics of . . . → Read More: Dynamic Ca2+-Dependent Stimulation of Vesicle Fusion by Membrane-Anchored Synaptotagmin 1

Shahaf Peleg,  Farahnaz Sananbenesi,  Athanasios Zovoilis,  Susanne Burkhardt, Sanaz Bahari-Javan, Roberto Carlos Agis-Balboa, Perla Cota, Jessica Lee Wittnam,  Andreas Gogol-Doering, Lennart Opitz, Gabriella Salinas-Riester, Markus Dettenhofer, Hui Kang, Laurent Farinelli, Wei Chen, André Fischer

As the human life span increases, the number of people suffering from cognitive decline is rising dramatically. The mechanisms underlying . . . → Read More: Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

Andrea Lorincz and Zoltan Nusser

Active invasion of the dendritic tree by action potentials (APs) generated in the axon is essential for associative synaptic plasticity and neuronal ensemble formation. In cortical pyramidal cells (PCs), this AP back-propagation is supported by dendritic voltage-gated Na+ (Nav) channels, whose molecular identity is unknown. Using a . . . → Read More: Molecular Identity of Dendritic Voltage-Gated Sodium Channels