By thirdrev, on June 2nd, 2010
Han-Ki Lee, Yoosoo Yang, Zengliu Su, Changbong Hyeon, Tae-Sun Lee, Hong-Won Lee, Dae-Hyuk Kweon, Yeon-Kyun Shin, Tae-Young Yoon
In neurons, synaptotagmin 1 (Syt1) is thought to mediate the fusion of synaptic vesicles with the plasma membrane when presynaptic Ca2+ levels rise. However, in vitro reconstitution experiments have failed to recapitulate key characteristics of . . . → Read More: Dynamic Ca2+-Dependent Stimulation of Vesicle Fusion by Membrane-Anchored Synaptotagmin 1
By thirdrev, on June 2nd, 2010
Shahaf Peleg, Farahnaz Sananbenesi, Athanasios Zovoilis, Susanne Burkhardt, Sanaz Bahari-Javan, Roberto Carlos Agis-Balboa, Perla Cota, Jessica Lee Wittnam, Andreas Gogol-Doering, Lennart Opitz, Gabriella Salinas-Riester, Markus Dettenhofer, Hui Kang, Laurent Farinelli, Wei Chen, André Fischer
As the human life span increases, the number of people suffering from cognitive decline is rising dramatically. The mechanisms underlying . . . → Read More: Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice