Induction of Fear Extinction with Hippocampal-Infralimbic BDNF

Jamie Peters, Laura M. Dieppa-Perea, Loyda M. Melendez, and Gregory J. Quirk

The extinction of conditioned fear memories requires plasticity in the infralimbic medial prefrontal cortex (IL mPFC), but little is known about the molecular mechanisms involved. Brain-derived neurotrophic factor (BDNF) is a key mediator of synaptic plasticity in multiple brain areas. . . . → Read More: Induction of Fear Extinction with Hippocampal-Infralimbic BDNF

The Fusogen EFF-1 Controls Sculpting of Mechanosensory Dendrites

Meital Oren-Suissa, David H. Hall, Millet Treinin, Gidi Shemer, and Benjamin Podbilewicz

The mechanisms controlling the formation and maintenance of neuronal trees are poorly understood. We examined the dynamic development of two arborized mechanoreceptor neurons (PVDs) required for reception of strong mechanical stimuli in Caenorhabditis elegans. The PVDs elaborated dendritic trees comprising . . . → Read More: The Fusogen EFF-1 Controls Sculpting of Mechanosensory Dendrites